One-Pot Cajun Chicken Alfredo

Featured in: One-Pot Comfort Meals

This one-pot dish blends tender chicken with smoky Cajun spices and a creamy Alfredo sauce to coat tender orzo pasta. Onions, garlic, and bell peppers build a flavorful base before the orzo simmers in a rich mixture of chicken broth and dairy. Finished with Parmesan and fresh parsley, it offers a comforting, quick meal packed with layers of bold and creamy flavors, perfect for busy weeknights.

Updated on Sun, 23 Nov 2025 11:07:00 GMT
Tender chicken pieces and creamy sauce mingle in this flavorful One-Pot Cajun Chicken Alfredo Orzo. Save
Tender chicken pieces and creamy sauce mingle in this flavorful One-Pot Cajun Chicken Alfredo Orzo. | cloverhearth.com

A creamy, spicy, and comforting one-pot meal combining tender chicken, smoky Cajun spices, velvety Alfredo sauce, and orzo pasta for a quick weeknight dinner.

I first served this to my family on a busy weeknight and they loved the perfect blend of spices and creamy texture that made dinner easy and delicious.

Ingredients

  • Proteins: 2 large boneless skinless chicken breasts (about 450 g) cut into bite sized pieces
  • Vegetables: 1 small yellow onion finely chopped 3 cloves garlic minced 1 red bell pepper diced 1 cup baby spinach roughly chopped (optional)
  • Pantry: 2 tablespoons olive oil 1 1/2 cups (300 g) orzo pasta 2 1/2 cups (600 ml) low sodium chicken broth 1 cup (240 ml) heavy cream 1/2 cup (120 ml) milk
  • Spices & Seasonings: 1 tablespoon Cajun seasoning (store bought or homemade) 1/2 teaspoon smoked paprika 1/2 teaspoon salt or to taste 1/4 teaspoon freshly ground black pepper Pinch of cayenne pepper (optional for extra heat)
  • Cheeses: 3/4 cup (75 g) freshly grated Parmesan cheese
  • Garnish: Chopped fresh parsley Extra Parmesan cheese

Instructions

Step 1:
Season the chicken pieces with half of the Cajun seasoning salt and pepper.
Step 2:
In a large deep skillet or Dutch oven heat olive oil over medium high heat Add the chicken and sauté until browned and just cooked through about 5 6 minutes Remove chicken to a plate and set aside.
Step 3:
In the same pot add onion and bell pepper Sauté for 3 minutes until softened Add garlic and cook for 1 minute more.
Step 4:
Stir in the orzo smoked paprika remaining Cajun seasoning and cayenne pepper Toast the orzo for 1 minute stirring frequently.
Step 5:
Pour in the chicken broth heavy cream and milk Stir well scraping any browned bits from the bottom.
Step 6:
Bring to a gentle boil then reduce heat to medium low Cover and simmer for 10 12 minutes stirring occasionally until orzo is tender and most liquid is absorbed.
Step 7:
Return the chicken to the pot along with spinach (if using) Stir in Parmesan cheese until melted and creamy.
Step 8:
Taste and adjust seasoning If sauce is too thick add a splash more milk or broth.
Step 9:
Serve hot garnished with parsley and extra Parmesan.
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| cloverhearth.com

This recipe always brings my family together around the table with smiles and full bellies after a long day.

Notes

For a lighter version use half and half instead of heavy cream Swap chicken with shrimp or smoked sausage for variation Add mushrooms or peas for extra vegetables Serve with crusty bread or a green salad

Required Tools

Large deep skillet or Dutch oven with lid Cutting board and knife Wooden spoon or spatula Measuring cups and spoons Grater (for Parmesan)

Allergen Information

Contains Dairy (cream milk Parmesan) Wheat (orzo) Possible Celery (in broth) Check Cajun seasoning and broth labels for hidden allergens

This image presents the finished One-Pot Cajun Chicken Alfredo Orzo, a satisfying dinner with a spicy aroma. Save
This image presents the finished One-Pot Cajun Chicken Alfredo Orzo, a satisfying dinner with a spicy aroma. | cloverhearth.com

This one pot Cajun chicken Alfredo orzo is sure to become a favorite for creamy and flavorful dinners that come together quickly.

Recipe Questions & Answers

Can I substitute chicken with other proteins?

Yes, shrimp or smoked sausage are excellent alternatives that complement the creamy, spicy sauce well.

Is baby spinach necessary in this dish?

Spinach is optional but adds a fresh, leafy texture and brightens the rich flavors.

How can I adjust the heat level?

Reduce or omit cayenne pepper or adjust the amount of Cajun seasoning to make it milder.

What can I use if I don't have orzo pasta?

Small pasta shapes like acini di pepe or Israeli couscous work well as substitutes.

How do I prevent the sauce from becoming too thick?

Add a splash of milk or chicken broth while cooking to maintain a creamy consistency.

One-Pot Cajun Chicken Alfredo

Comforting one-pot dish blending chicken, Cajun spices, creamy Alfredo, and tender orzo pasta in one skillet.

Prep duration
15 minutes
Cook duration
25 minutes
Overall time
40 minutes
Recipe by Clover Hearth Emily Dawson

Recipe type One-Pot Comfort Meals

Skill level Easy

Culinary roots American, Cajun-Inspired

Servings made 4 Portion size

Diet preferences None specified

What you'll need

Proteins

01 2 large boneless, skinless chicken breasts (about 16 oz), cut into bite-sized pieces

Vegetables

01 1 small yellow onion, finely chopped
02 3 cloves garlic, minced
03 1 red bell pepper, diced
04 1 cup baby spinach, roughly chopped (optional)

Pantry

01 2 tablespoons olive oil
02 1 1/2 cups orzo pasta (about 10.5 oz)
03 1 cup plus 1/8 cup low-sodium chicken broth (20 fl oz)
04 1 cup heavy cream (8 fl oz)
05 1/2 cup milk (4 fl oz)

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon salt, or to taste
04 1/4 teaspoon freshly ground black pepper
05 Pinch of cayenne pepper (optional)

Cheeses

01 3/4 cup freshly grated Parmesan cheese (2.6 oz)

Garnish

01 Chopped fresh parsley
02 Extra Parmesan cheese

How to make it

Step 01

Season chicken: Combine chicken pieces with half the Cajun seasoning, salt, and pepper. Set aside.

Step 02

Sauté chicken: Heat olive oil in a large deep skillet or Dutch oven over medium-high heat. Add chicken and cook until browned and just cooked through, about 5 to 6 minutes. Remove and set aside.

Step 03

Cook vegetables: In the same pot, add onion and bell pepper. Sauté for 3 minutes until softened. Add garlic and cook for 1 minute more.

Step 04

Toast orzo and spices: Stir in orzo, smoked paprika, remaining Cajun seasoning, and cayenne pepper. Toast for 1 minute, stirring frequently.

Step 05

Add liquids: Pour in chicken broth, heavy cream, and milk. Stir well, scraping browned bits from the bottom.

Step 06

Simmer orzo: Bring to a gentle boil. Reduce heat to medium-low, cover, and simmer 10 to 12 minutes, stirring occasionally, until orzo is tender and most liquid absorbed.

Step 07

Finish dish: Return chicken and spinach (if used) to pot. Stir in Parmesan cheese until melted and creamy.

Step 08

Adjust seasoning: Taste and modify seasoning as needed. Thin sauce with milk or broth if too thick.

Step 09

Serve: Serve immediately, garnished with parsley and extra Parmesan cheese.

Equipment needed

  • Large deep skillet or Dutch oven with lid
  • Cutting board and knife
  • Wooden spoon or spatula
  • Measuring cups and spoons
  • Grater for Parmesan cheese

Allergy details

Be sure to review every ingredient for potential allergies, and talk to a medical expert if you’re unsure.
  • Contains dairy: cream, milk, Parmesan
  • Contains wheat: orzo pasta
  • Possible celery in broth

Nutrition information (each portion)

Only use this data as a helpful reference—it’s not intended to replace professional health guidance.
  • Calorie count: 570
  • Fat content: 27 grams
  • Carbohydrates: 48 grams
  • Proteins: 37 grams