Zesty Cajun Garlic Parmesan Chicken

Featured in: Warm Family Dinners

This dish combines tender pieces of chicken with cheesy tortellini, enveloped in a creamy sauce infused with Cajun spices, garlic, and Parmesan. Sautéed onions, bell peppers, and aromatic garlic build depth, while smoked paprika adds a subtle smoky note. Finished with fresh parsley, this flavorful meal comes together quickly, balancing creamy, spicy, and savory elements for an easy, satisfying dinner option.

Updated on Sat, 15 Nov 2025 09:47:00 GMT
Zesty Cajun Garlic Parmesan Chicken Tortellini: creamy pasta dish with tender chicken, ready to serve with parsley. Save
Zesty Cajun Garlic Parmesan Chicken Tortellini: creamy pasta dish with tender chicken, ready to serve with parsley. | cloverhearth.com

A vibrant and flavorful pasta dish combining tender chicken, cheesy tortellini, and a creamy Cajun garlic Parmesan sauce. This meal is perfect for those looking for a quick weeknight dinner with a spicy kick and comforting twist.

I first made this for a busy Wednesday night when everyone wanted something hearty but with a little zing. The combination of Cajun seasoning and Parmesan was a hit with my family and has become a much-requested meal ever since.

Ingredients

  • Boneless, skinless chicken breasts: 2 large, cut into bite sized pieces
  • Refrigerated cheese tortellini: 500 g (18 oz)
  • Garlic: 3 cloves, minced
  • Red bell pepper: 1 small, diced
  • Yellow onion: 1 small, diced
  • Heavy cream: 1 cup (240 ml)
  • Parmesan cheese: 1/2 cup (50 g), freshly grated
  • Unsalted butter: 2 tablespoons
  • Cajun seasoning: 1 tablespoon
  • Smoked paprika: 1/2 teaspoon
  • Black pepper: 1/2 teaspoon
  • Salt: 1/2 teaspoon, plus more to taste
  • Olive oil: 2 tablespoons
  • Fresh parsley: 2 tablespoons, chopped for garnish
  • Optional grated Parmesan: extra for serving

Instructions

Cook tortellini:
Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.
Sauté chicken:
Heat 1 tablespoon olive oil in a large skillet over medium high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5 minutes. Remove chicken and set aside.
Sauté vegetables:
In the same skillet add remaining olive oil and butter. Sauté onion and bell pepper for 3 minutes until softened. Add garlic and cook for 30 seconds until fragrant.
Add spices and cream:
Sprinkle in remaining Cajun seasoning and smoked paprika. Stir, then pour in the heavy cream. Bring to a gentle simmer, stirring frequently.
Melt Parmesan:
Add Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning if needed.
Combine chicken and pasta:
Return chicken to the skillet, along with cooked tortellini. Toss gently to coat in the sauce.
Heat through and serve:
Cook for an additional 2 minutes until heated through. Serve garnished with fresh parsley and extra Parmesan if desired.
A steaming bowl of Zesty Cajun Garlic Parmesan Chicken Tortellini showcases hearty ingredients and cheesy goodness. Save
A steaming bowl of Zesty Cajun Garlic Parmesan Chicken Tortellini showcases hearty ingredients and cheesy goodness. | cloverhearth.com

This dish quickly became a family favorite, especially on chilly nights when a creamy spicy pasta brings everyone together at the dinner table.

Required Tools

Large pot, large skillet, chefs knife, cutting board, wooden spoon or spatula, measuring cups and spoons

Allergen Information

Contains: Wheat (tortellini), milk (cream, Parmesan, butter), eggs (tortellini). Double check tortellini packaging for specifics.

Nutritional Information (per serving)

Calories: 620. Total fat: 29 g. Carbohydrates: 53 g. Protein: 38 g.

Imagine this: perfectly cooked Zesty Cajun Garlic Parmesan Chicken Tortellini, fragrant with spicy Cajun spices and garlic. Save
Imagine this: perfectly cooked Zesty Cajun Garlic Parmesan Chicken Tortellini, fragrant with spicy Cajun spices and garlic. | cloverhearth.com

Enjoy this bold fusion of flavors for dinner tonight. It makes fantastic leftovers, reheating beautifully in a skillet the next day.

Recipe Questions & Answers

What pasta works best in this dish?

Cheese tortellini is ideal, as its filled texture complements the creamy sauce perfectly.

Can I adjust the spice level?

Yes, adding cayenne pepper or red pepper flakes increases heat, while reducing Cajun seasoning tones it down.

Is there a seafood alternative?

Substituting shrimp for chicken offers a delicious seafood variation with similar cooking times.

How can I make the sauce thicker?

Simmer the sauce gently, allowing cream and Parmesan to meld and thicken naturally without overcooking.

What side pairs well with this dish?

Crusty bread soaks up the sauce nicely and a crisp white wine like Sauvignon Blanc complements the flavors.

Zesty Cajun Garlic Parmesan Chicken

A vibrant dish with tender chicken, cheesy tortellini, and a creamy Cajun garlic Parmesan sauce.

Prep duration
15 minutes
Cook duration
25 minutes
Overall time
40 minutes
Recipe by Clover Hearth Emily Dawson

Recipe type Warm Family Dinners

Skill level Easy

Culinary roots American/Italian Fusion

Servings made 4 Portion size

Diet preferences None specified

What you'll need

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 18 oz refrigerated cheese tortellini

Vegetables & Aromatics

01 3 cloves garlic, minced
02 1 small red bell pepper, diced
03 1 small yellow onion, diced

Dairy

01 1 cup heavy cream
02 1/2 cup freshly grated Parmesan cheese
03 2 tablespoons unsalted butter

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon black pepper
04 1/2 teaspoon salt, plus more to taste

Oils & Garnish

01 2 tablespoons olive oil
02 2 tablespoons chopped fresh parsley (for garnish)

How to make it

Step 01

Cook tortellini: Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.

Step 02

Sauté chicken: Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and black pepper. Sauté until browned and cooked through, approximately 5 to 7 minutes. Remove chicken from skillet and set aside.

Step 03

Cook vegetables: In the same skillet, add remaining olive oil and butter. Sauté diced onion and bell pepper for 3 to 4 minutes until softened. Add minced garlic and cook for 30 seconds until fragrant.

Step 04

Prepare sauce: Sprinkle remaining Cajun seasoning and smoked paprika over vegetables. Stir well, then pour in heavy cream. Bring to a gentle simmer, stirring frequently.

Step 05

Incorporate cheese: Stir in Parmesan cheese until fully melted and sauce achieves a smooth consistency. Adjust seasoning to taste if necessary.

Step 06

Combine ingredients: Return cooked chicken and tortellini to the skillet. Toss gently to coat all components evenly with the sauce.

Step 07

Finish cooking: Cook for an additional 2 to 3 minutes to ensure everything is heated through.

Step 08

Serve: Plate the dish and garnish with fresh parsley and optional extra grated Parmesan as desired.

Equipment needed

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Measuring cups and spoons

Allergy details

Be sure to review every ingredient for potential allergies, and talk to a medical expert if you’re unsure.
  • Contains wheat (tortellini), milk (cream, Parmesan, butter), and possibly eggs (tortellini). Verify packaging for specifics.

Nutrition information (each portion)

Only use this data as a helpful reference—it’s not intended to replace professional health guidance.
  • Calorie count: 620
  • Fat content: 29 grams
  • Carbohydrates: 53 grams
  • Proteins: 38 grams